http://www.cbisociety.org/backend/ CBIS en-us Wed, 22 Feb 2006 19:40:25 GMT 1440 CPG-Nuke Dragonfly Chinese Biological Investigators Society News http://backend.userland.com/rss http://www.cbisociety.org/backend/images/logo.gif http://www.cbisociety.org/backend/ http://www.cbisociety.org/backend/index.php?name=News&file=article&sid=4 Apoptosis, executed by caspases (cysteine proteases with aspartate substrate specificity), plays a central role in the development and homeostasis of all multi-cellular organisms. In mammals, the BH3-only proteins (such as Bid and Bim) transduce the signal to mitochondria after receiving apoptotic stimuli (Figure 1). The release of mitochondrial proteins (such as cytochrome c) is mediated by Bak and Bax, the pro-apoptotic members of the Bcl-2 family of proteins. Once in the cytosol, cytochrome c associates with Apaf-1 in the presence of dATP or ATP, which further mediates the activation of the initiator caspase-9. The activated caspase-9 in turn cleaves and activates the effector caspases, caspase-3 and caspase-7. Wed, 22 Feb 2006 19:40:25 GMT http://www.cbisociety.org/backend/index.php?name=News&file=article&sid=3 Professor Zuoyan Zhu, Vice Director of the National Natural Sciences Foundation of China and a member of the China Academy of Sciences, has received Ray Wu Award from the CBI Society during the 2005 society meeting for his outstanding contributions to the advancement of life sciences in China and to the enhancement of international scientific exchanges. Wed, 22 Feb 2006 14:12:56 GMT http://www.cbisociety.org/backend/index.php?name=News&file=article&sid=2 02/21/06 -- Vical Incorporated (Nasdaq: VICL) announced today that an Ebola vaccine candidate administered using Vical's proprietary DNA delivery technology was safe and well tolerated, and produced both antibody and T-cell Ebola-specific responses in all healthy volunteers who received the full 3 doses of vaccine. Source: Vical Incorporated Wed, 22 Feb 2006 14:04:21 GMT